Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates /

Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates reviews how the use of these techniques on compounds with already known and relevant biological activity can provide new pharmaceutical leads with improved medicinal properties. The fluorination strategies discussed...

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Main Author: Postigo, Al, (Author)
Language:English
Published: Amsterdam, Netherlands : Elsevier, [2019]
Subjects:
Online Access:ScienceDirect
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020 |a 9780128129586 
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100 1 |a Postigo, Al,  |e author. 
245 1 0 |a Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates /  |c Al Postigo. 
264 1 |a Amsterdam, Netherlands :  |b Elsevier,  |c [2019] 
300 |a 1 online resource :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
588 0 |a Online resource; title from PDF title page (EBSCO, viewed September 18, 2018). 
520 |a Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates reviews how the use of these techniques on compounds with already known and relevant biological activity can provide new pharmaceutical leads with improved medicinal properties. The fluorination strategies discussed take into account both conventional and novel reagents, including nucleophilic, electrophilic, those of a radical nature, and diverse families of organic compounds, such as (hetero) aromatic rings and aliphatic substrates. Drawing on the authors' expert knowledge, this book provides researchers with a broad set of applicable methods to use in their work. 
650 0 |a Fluorination. 
650 0 |a Biomolecules. 
650 7 |a SCIENCE / Chemistry / Organic.  |2 bisacsh 
650 7 |a Biomolecules.  |2 fast  |0 (OCoLC)fst00832624 
650 7 |a Fluorination.  |2 fast  |0 (OCoLC)fst00928150 
655 0 |a Electronic books. 
655 4 |a Electronic books. 
856 4 0 |3 ScienceDirect  |u https://www.sciencedirect.com/science/book/9780128129586