02432cam a2200481Ii 4500 on1052566523 OCoLC 20210423014330.0 m o d cr cnu|||unuuu 180914s2019 ne a ob 001 0 eng d N$T eng rda pn N$T N$T NLE OCLCF COO OPELS UKMGB MERER D6H OCLCQ N$T LQU S2H OCLCO LVT GBB8H4781 bnb 019053477 Uk 019053477 1105176166 1105566024 1229809000 9780128130391 (electronic bk.) 0128130393 (electronic bk.) 9780128129586 0128129581 9780128129586 (OCoLC)1052566523 (OCoLC)1105176166 (OCoLC)1105566024 (OCoLC)1229809000 QD281.F55 SCI 013040 bisacsh 547/.2 23 Postigo, Al, author. Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates / Al Postigo. Amsterdam, Netherlands : Elsevier, [2019] 1 online resource : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier Includes bibliographical references and index. Online resource; title from PDF title page (EBSCO, viewed September 18, 2018). Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates reviews how the use of these techniques on compounds with already known and relevant biological activity can provide new pharmaceutical leads with improved medicinal properties. The fluorination strategies discussed take into account both conventional and novel reagents, including nucleophilic, electrophilic, those of a radical nature, and diverse families of organic compounds, such as (hetero) aromatic rings and aliphatic substrates. Drawing on the authors' expert knowledge, this book provides researchers with a broad set of applicable methods to use in their work. Fluorination. Biomolecules. SCIENCE / Chemistry / Organic. bisacsh Biomolecules. fast (OCoLC)fst00832624 Fluorination. fast (OCoLC)fst00928150 Electronic books. Electronic books. ScienceDirect https://www.sciencedirect.com/science/book/9780128129586