Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates /

Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates reviews how the use of these techniques on compounds with already known and relevant biological activity can provide new pharmaceutical leads with improved medicinal properties. The fluorination strategies discussed...

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Main Author: Postigo, Al, (Author)
Language:English
Published: Amsterdam, Netherlands : Elsevier, [2019]
Subjects:
Online Access:ScienceDirect
Summary:Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates reviews how the use of these techniques on compounds with already known and relevant biological activity can provide new pharmaceutical leads with improved medicinal properties. The fluorination strategies discussed take into account both conventional and novel reagents, including nucleophilic, electrophilic, those of a radical nature, and diverse families of organic compounds, such as (hetero) aromatic rings and aliphatic substrates. Drawing on the authors' expert knowledge, this book provides researchers with a broad set of applicable methods to use in their work.
Physical Description:1 online resource : illustrations
Bibliography:Includes bibliographical references and index.
ISBN:9780128130391
0128130393
0128129581
9780128129586