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05528cam a2200613Ii 4500 |
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on1039079230 |
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OCoLC |
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20210423014327.0 |
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m o d |
| 007 |
cr cnu|||unuuu |
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180607s2018 ne a ob 001 0 eng d |
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|a N$T
|b eng
|e rda
|e pn
|c N$T
|d N$T
|d OPELS
|d YDX
|d EBLCP
|d MERER
|d OCLCF
|d COO
|d OCLCQ
|d OTZ
|d NLE
|d INT
|d SNK
|d OCLCQ
|d UKMGB
|d U3W
|d LVT
|d OCLCQ
|d D6H
|d LQU
|d OCLCQ
|d S2H
|d OCLCO
|d UX1
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7 |
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|a 018870091
|2 Uk
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| 019 |
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|a 1039674533
|a 1105170402
|a 1105562504
|a 1229568894
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|a 9780128112939
|q (electronic bk.)
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|a 012811293X
|q (electronic bk.)
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|z 9780128112922
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| 020 |
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|z 0128112921
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| 035 |
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|a (OCoLC)1039079230
|z (OCoLC)1039674533
|z (OCoLC)1105170402
|z (OCoLC)1105562504
|z (OCoLC)1229568894
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4 |
|a QD505
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|a SCI
|x 013050
|2 bisacsh
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|a 541/.395
|2 23
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| 245 |
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|a Palladium-catalyzed modification of nucleosides, nucleotides and oligonucleotides /
|c edited by Anant R. Kapdi, Debabrata Maiti, Yogesh S. Sanghvi.
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| 264 |
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1 |
|a Amsterdam, Netherlands :
|b Elsevier,
|c [2018]
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| 300 |
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|a 1 online resource :
|b illustrations
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| 336 |
|
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|a text
|b txt
|2 rdacontent
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| 337 |
|
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|a computer
|b c
|2 rdamedia
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| 338 |
|
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Latest trends in palladium chemistry
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| 504 |
|
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|a Includes bibliographical references and index.
|
| 588 |
0 |
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|a Online resource; title from PDF title page (EBSCO, viewed June 11, 2018).
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| 505 |
0 |
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|a Front Cover; Palladium-Catalyzed Modification of Nucleosides, Nucleotides and Oligonucleotides; Copyright; Contents; Contributors; Chapter 1: The Future of Drug Discovery: The Importance of Modified Nucleosides, Nucleotides, and Oligonucleotides; 1. Introduction; 2. Biologically Active Modified Nucleosides; 3. Synthetic Fluorescent Nucleoside Analogs; 4. Oligonucleotide Applications; 5. An Overview of Other Cross-Coupling Reactions in This Book; 6. Stille Cross-Coupling; 7. Suzuki-Miyaura Cross-Coupling; 8. Sonogashira reactions; 9. Heck Cross-Coupling.
|
| 505 |
8 |
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|a 10. Buchwald-Hartwig reactions11. C-H Activation Reactions; 12. Cross-Coupling of Nucleotides and Oligonucleotides; 13. Summary and Future Directions; References; Chapter 2: Stille Cross-Coupling Reaction: Early Years to the Current State of the Art; 1 Introduction; 2. Stille Coupling Reactions; 2.1 Early Developments; 3 Conclusion; References; Chapter 3: Suzuki-Miyaura Cross-Coupling as a Synthetic Tool for Nucleoside and Nucleotide Modification; 1. Introduction; 2. Suzuki-Miyaura Reaction: Mechanism and Conditions; 2.1 Overview of the Reaction.
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| 505 |
8 |
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|a 2.2 Suzuki-Miyaura Reaction in Various Water-Based Catalytic Systems2.2.1 In Tetrahydrofuran/Methanol/Water; 2.2.2 In Dimethylether/Water; 2.2.3 In DMF/H2O; 2.2.4 In ACN/H2O; 2.2.5 In MeOH/H2O; 2.2.6 In H2O; 3. Palladium-Catalyzed Suzuki-Miyaura Routes to Modified Nucleosides; 3.1 Purine Nucleoside Analogues; 3.1.1 Modified Nucleosides at Purine Moiety; 3.1.2 Modified Flexible Nucleosides; 3.1.3 Carbocyclic Nucleosides Analogues; 3.2 Pyrimidine-Modified Analogues; 3.2.1 Arylation at C5- and C6- of Uridine/Cytidine Moiety.
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| 505 |
8 |
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|a 3.2.2 Arylation of C5-Halo Uridine/Cytidine and C7-Halo Purine Nucleotides3.3 Miscellaneous; 4. Concluding Remarks; Acknowledgments; References; Chapter 4: Sonogashira Cross-Coupling: Alkyne-Modified Nucleosides and Their Applications; 1. Introduction; 2. General Reaction and the Mechanism of Classical Sonogashira Reaction; 3. Modifications of Sonogashira Coupling; 3.1 Modifications of Ligated Pd-Catalysts; 3.2 Generation of Ligand-Free Palladium Catalysts; 3.3 Palladium Nanoparticles as Catalysts.
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| 505 |
8 |
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|a 3.4 Modified Form of Cu(I)-Co-Catalyst: Click Reagent Version of Sonogashira Coupling: Contribution From Our Group3.5 Cu-Free Sonogashira Coupling; 3.6 Ligand, Copper, and Amine-Free Palladium Catalyzed Sonogashira Coupling; 4. Applications of the Sonogashira Reaction; 5. Sonogashira Reaction in the Synthesis of Nucleoside; 6. Application of Sonogashira Coupling to Pyrimidine Nucleosides; 6.1 Synthesis of C-4-Substituted Pyrimidines; 6.2 Synthesis of C-5-Substituted Pyrimidines; 7. Sonogashira Coupling for the Synthesis of Substituted Purine Nucleosides.
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| 520 |
8 |
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|a Annotation
|b This volume describes the procedures and protocols related to the modification of nucleosides, nucleotides and oligonucleotides via Pd-mediated cross-coupling processes. The book highlights the growing area of nucleic acid modification and how Pd-mediated coupling reactions can assist this development.
|
| 650 |
|
0 |
|a Palladium catalysts.
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| 650 |
|
0 |
|a Nucleosides.
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| 650 |
|
0 |
|a Nucleotides.
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| 650 |
|
0 |
|a Oligonucleotides.
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| 650 |
|
7 |
|a SCIENCE
|x Chemistry
|x Physical & Theoretical.
|2 bisacsh
|
| 650 |
|
7 |
|a Nucleosides.
|2 fast
|0 (OCoLC)fst01041098
|
| 650 |
|
7 |
|a Nucleotides.
|2 fast
|0 (OCoLC)fst01041118
|
| 650 |
|
7 |
|a Oligonucleotides.
|2 fast
|0 (OCoLC)fst01045453
|
| 650 |
|
7 |
|a Palladium catalysts.
|2 fast
|0 (OCoLC)fst01051700
|
| 655 |
|
0 |
|a Electronic books.
|
| 655 |
|
4 |
|a Electronic books.
|
| 700 |
1 |
|
|a Kapdi, Anant R.,
|e editor.
|
| 700 |
1 |
|
|a Maiti, Debabrata,
|e editor.
|
| 700 |
1 |
|
|a Sanghvi, Yogesh S.,
|d 1956-
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|t Palladium-catalyzed modification of nucleosides, nucleotides and oligonucleotides.
|d Amsterdam, Netherlands : Elsevier, [2018]
|z 9780128112922
|z 0128112921
|w (OCoLC)1002834729
|
| 830 |
|
0 |
|a Latest trends in palladium chemistry.
|
| 856 |
4 |
0 |
|3 ScienceDirect
|u https://www.sciencedirect.com/science/book/9780128112922
|
