Insights into Human Neurodegeneration: Lessons Learnt from Drosophila

This book is aimed at generating an updated reservoir of scientific endeavors undertaken to unravel the complicated yet intriguing topic of neurodegeneration. Scientists from Europe, USA and India who are experts in the field of neurodegenerative diseases have contributed to this book. This book wil...

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Corporate Author: SpringerLink (Online service)
Other Authors: Mutsuddi, Mousumi. (Editor, http://id.loc.gov/vocabulary/relators/edt), Mukherjee, Ashim. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Language:English
Published: Singapore : Springer Singapore : Imprint: Springer, 2019.
Edition:1st ed. 2019.
Subjects:
Online Access:https://doi.org/10.1007/978-981-13-2218-1
Table of Contents:
  • Chapter 1. Introduction to Drosophila as a model organism
  • Chapter 2. Methods for creating fly models in order to understand molecular mechanism of neurological diseases
  • Chapter 3. Neurodegeneration: Lessons learnt from forward genetic screens in Drosophila
  • Chapter 4. Drosophila neural stem cells, a primer for understanding mammalian neurobiology
  • Chapter 5. Understanding motor disorders using flies
  • Chapter 6. Metabolic alterations amalgamated with neurodegenerative diseases
  • Chapter 7. Notch signalling in neurodegenerative disease
  • Chapter 8. Drosophila model of neurofibrillar tangles
  • Chapter 9. Unraveling Alzheimer's disease using Drosophila
  • Chapter 10. Modelling Human Parkinson's disease in fly
  • Chapter 11. Post-translational modifications: A mystery to unravel Huntington’s disease
  • Chapter 12. Understanding the pathogenicity of non-coding RNA expansion associated neurodegenerative disorders
  • Chapter 13. Expanding roles of RNA binding proteins in neurodegeneration
  • Chapter 14. Hereditary Spastic Paraplegia Disease in Drosophila
  • Chapter 15. Drosophila as a model system for the identification of pharmacological therapies in neurodegenerative diseases.