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Cystogenesis

This book covers the mechanisms of renal cyst development as well as the aberrant signaling pathways which are involved in Autosomal Dominant Polycystic Kidney Disease (ADPKD). ADPKD is a genetic disease in which cysts appear in the epithelial lining of both kidneys. End stage ADPKD patients experie...

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Corporate Author: SpringerLink (Online service)
Other Authors: Park, Jong Hoon. (Editor, http://id.loc.gov/vocabulary/relators/edt), Ahn, Curie. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Language:English
Published: Singapore : Springer Singapore : Imprint: Springer, 2016.
Edition:1st ed. 2016.
Series:Advances in Experimental Medicine and Biology, 933
Subjects:
Human genetics.
Molecular biology.
Cell biology.
Medical microbiology.
Human Genetics.
Molecular Medicine.
Cell Biology.
Medical Microbiology.
Online Access:https://doi.org/10.1007/978-981-10-2041-4
Table of Contents:
  • Part I ADPKD Overview
  • Chapter 1 Recent Trends in ADPKD Research
  • Chapter 2 Genetic Mechanisms of ADPKD
  • Part II Cystogenesis Mechanisms
  • Chapter 3 Cell Proliferation and Apoptosis in ADPKD
  • Chapter 4 Inflammation and Fibrosis in ADPKD
  • Chapter 5 Functional Study of the Primary Cilia in ADPKD
  • Chapter 6 Epigenetic Regulation in Cystogenesis
  • Part III Therapeutic Approaches and Diagnostic Markers for ADPKD
  • Chapter 7 Validation of Effective Therapeutic Targets for ADPKD using Animal Models
  • Chapter 8 Diagnostic Evaluation as a Biomarker in Patients with ADPKD
  • Chapter 9 Clinical Trials and a View toward the Future of ADPKD.

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