Cytochrome P450 2E1: Its Role in Disease and Drug Metabolism
The book deals with various clinical aspects of cytochrome P450 2E1 (CYP2E1), which is a potent source for oxidative stress. Oxidative stress is critical for pathogenesis of diseases and CYP2E1 is a major contributor for oxidative stress. Several clinical disorders are associated with changes in reg...
| Corporate Author: | |
|---|---|
| Other Authors: | |
| Language: | English |
| Published: |
Dordrecht :
Springer Netherlands : Imprint: Springer,
2013.
|
| Edition: | 1st ed. 2013. |
| Series: | Subcellular Biochemistry,
67 |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/978-94-007-5881-0 |
Table of Contents:
- Cytochrome P450 2E1 and its clinical aspects
- Nrf2 and antioxidant defense against CYP2E1 toxicity
- The role of Cytochrome P-4502E1 in ethanol-mediated carcinogenesis
- The Importance of CYP2E1 in the pathogenesis of alcoholic liver disease and drug toxicity and the role of the proteasome
- Relevance of CYP2E1 to non-alcoholic fatty liver disease
- CYP2E1-catalyzed alcohol metabolism
- CYP2E1, oxidative stress, post-translational modifications and lipid metabolism
- The role of CYP2E1 in alcohol metabolism and sensitivity in the central nervous system.