Glycosignals in Cancer: Mechanisms of Malignant Phenotypes

This book is a collection of cutting-edge studies on the functions and mechanisms of glycosylation in cancers. Along with progress in genomics and proteomics, new findings in the significance of these complex carbohydrates, through the regulation of cell signals, have been elucidated in a wide varie...

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Corporate Author: SpringerLink (Online service)
Other Authors: Furukawa, Koichi. (Editor, http://id.loc.gov/vocabulary/relators/edt), Fukuda, Minoru. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Language:English
Published: Tokyo : Springer Japan : Imprint: Springer, 2016.
Edition:1st ed. 2016.
Subjects:
Online Access:https://doi.org/10.1007/978-4-431-55939-9
Table of Contents:
  • Part 1 Changes of Glycosylation Machineries in Cancer Cells
  • 1 Roles of Fucosyltransferases in Cancer Phenotypes
  • 2 Glycosyltransferases and Gastric Cancer
  • Part 2 Regulation of Cancer Phenotypes by Carbohydrates
  • 3 Differential Roles of Mammalian Sialidases in Cancers
  • Part 3 Altered Cell Signaling in Cancer Cells
  • 4 Regulatory Mechanisms for Malignant Properties of Cancer Cells with Disialyl and Monosialyl Gangliosides
  • 5 Regulation of Growth Factor Receptors by Glycosphingolipids
  • 6 Nutrient Regulation of Cancer Cells by O-GlcNAcylation
  • Part 4 Regulation of Immune Systems and Cancers by Carbohydrates
  • 7 Function of Unique O-Glycan Structures in Protecting Gastric Mucosa Against Helicobacter pylori Infection and Gastric Cancer Development
  • 8 Sialylation and Immune Surveillance of Cancer by Siglecs
  • Part 5 Changes in the Organization of Complex Carbohydrates in Cancers
  • 9 Expression and Function of Poly-N-Acetyllactosamine Type Glycans in Cancer
  • 10 Role of Glycans in Cancer Cell Death: A Deadly Relationship
  • Part 6 Implication of Sugars in Cancer Diagnostics and Therapeutics
  • 11 Targeting Glycans for Immunotherapy of Human Cancers.