Amebiasis Biology and Pathogenesis of Entamoeba /

This book documents and presents new developments in the study of amebiasis, one of the neglected tropical diseases. Nearly 50 million people worldwide are infected with the pathogen Entamoeba histolytica, causing large-scale morbidity and mortality particularly in developing countries. This book wi...

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Corporate Author: SpringerLink (Online service)
Other Authors: Nozaki, Tomoyoshi. (Editor, http://id.loc.gov/vocabulary/relators/edt), Bhattacharya, Alok. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Language:English
Published: Tokyo : Springer Japan : Imprint: Springer, 2015.
Edition:1st ed. 2015.
Subjects:
Online Access:https://doi.org/10.1007/978-4-431-55200-0
Table of Contents:
  • Preface
  • 1 Introduction
  • 2 The continuously expanding universe of Entamoeba
  • 3 The genomics of Entamoebae: insights and challenges
  • 4 Multilocus sequence typing system (MLST): Genetic diversity and genetic components to virulence
  • 5 The tRNA gene-linked STRs and other genetic typing methods
  • 6 Genetic manipulation techniques
  • 7 Surveying Entamoeba histolytica transcriptome using massively parallel cDNA sequencing
  • 8 Ribosomal RNA Genes and their Regulation in Entamoeba histolytica
  • 9 Small RNAs and regulation of gene expression in Entamoeba histolytica
  • 10 The Biology of Retrotransposition in Entamoeba histolytica
  • 11 Entamoeba histolytica: Bridging the gap between environmental stress and epigenetic regulation
  • 12 Phagocytosis in Entamoeba histolytica
  • 13 Signalling pathways in E. histolytica
  • 14 Transmembrane Kinases and their role in E. histolytica pathogenesis
  • 15 Cell surface molecules as virulence determinants in Entamoeba histolytica
  • 16 Mechanism of cell division in Entamoeba histolytica
  • 17 Molecular basis of the trafficking of cysteine proteases and other soluble lysosomal proteins in Entamoeba histolytica
  • 18 Mitosomes in Entamoeba histolytica
  • 19 Metabolomic analysis of Entamoeba biology
  • 20 Glucose metabolism and its controlling mechanisms in Entamoeba histolytica
  • 21 Structural Biology of Cysteine Biosynthetic Pathway Enzymes
  • 22 Archetypical and specialized DNA replication proteins in Entamoeba histolytica
  • 23 Pathology, pathogenesis and experimental amebiasis
  • 24 Innate Host Defenses in the Gut
  • 25 Cysteine peptidases in pathogenesis
  • 26 Host immunity and tissue destruction during liver abscess formation
  • 27 The Effect of E. histolytica on Muc2 Mucin and Intestinal Permeability
  • 28 Human Genetic Susceptibility to Amebiasis
  • 29 Immune Response in Human Amoebiasis: a protective response?
  • 30 Metronidazole and the Redox Biochemistry of Entamoeba histolytica
  • 31 Thioredoxin Reductase and its Role as a New Drug Target
  • 32 Drug development: old drugs and new lead
  • 33 HETEROCYCLIC LEAD COMPOUNDS AGAINST AMOEBIASIS.