Adhesion Molecules: Function and Inhibition
Inflammatory cell recruitment requires the concerted action of at least five major sets of adhesion molecules: integrins, immunoglobulin-like molecules, selectins, carbohydrate structures serving as selectin ligands, and certain ectoenzymes. This volume gives a comprehensive overview on the most rel...
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| Language: | English |
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Basel :
Birkhäuser Basel : Imprint: Birkhäuser,
2007.
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| Edition: | 1st ed. 2007. |
| Series: | Progress in Inflammation Research,
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| Online Access: | https://doi.org/10.1007/978-3-7643-7975-9 |
Table of Contents:
- Capture and rolling
- P-selectin glycoprotein ligand-1 (PSGL-1)
- L-selectin-mediated leukocyte adhesion and migration
- P- and E-selectin
- Firm adhesion
- Endothelial ICAM-1 functions in adhesion and signaling during leukocyte recruitment
- ?4-integrins: structure, function and secrets
- VCAM-1 and its functions in development and inflammatory diseases
- Lymphocyte function-associated antigen-1 (LFA-1) and macrophage antigen-1 (Mac-1): Cooperative partners in leukocyte emigration and function
- Transendothelial migration
- PECAM: Regulating the start of diapedesis
- Role of ?6?1 integrin in leukocyte adhesion and transmigration
- Vascular adhesion protein-1 (VAP-1)
- The role of endothelial cell-selective adhesion molecule (ESAM) in neutrophil emigration into inflamed tissues
- Structure and function of JAM proteins
- Promises and limitations of targeting adhesion molecules for therapy.