Behavioral Neurobiology of Huntington's Disease and Parkinson's Disease

Motor dysfunction and cognitive impairment are major symptoms in both Huntington’s Disease (HD) and Parkinson’s Disease (PD). A breakthrough in HD research occurred in 1993, with the identification of the gene causing this devastating monogenetic illness. Since 1996, several genes were reported to c...

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Corporate Author: SpringerLink (Online service)
Other Authors: Nguyen, Hoa Huu Phuc. (Editor, http://id.loc.gov/vocabulary/relators/edt), Cenci, M. Angela. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2015.
Edition:1st ed. 2015.
Series:Current Topics in Behavioral Neurosciences, 22
Subjects:
Online Access:https://doi.org/10.1007/978-3-662-46344-4
Table of Contents:
  • Clinical Aspects of Huntington’s Disease
  • The Neuropathology of Huntington’s Disease
  • Neurobiology of Huntington’s Disease
  • Mouse Models of Huntington’s Disease
  • Transgenic Rat Models of Huntington’s Disease
  • Large Animal Models of Huntington’s Disease
  • Therapeutic Strategies for Huntington’s Disease
  • Clinical and Pathological Features of Parkinson’s Disease
  • Symptomatic Models of Parkinson’s Disease and L-DOPA-Induced Dyskinesia in Non-human Primates
  • Neuroinflammation in Parkinson’s Disease Animal Models: A Cell Stress Response or a Step in Neurodegeneration?
  • Viral Vector-Based Models of Parkinson’s Disease
  • Transgenic Rodent Models to Study Alpha-Synuclein Pathogenesis, with a Focus on Cognitive Deficits
  • Modeling LRRK2 Pathobiology in Parkinson’s Disease: From Yeast to Rodents
  • Models of Multiple System Atrophy.