Genetic Control of Neuronal Migrations in Human Cortical Development
1 Introduction Cortical development is a complex, tightly regulated process that eventually leads to the six-layered adult human neocortex, the substrate of the unique cognitive, emotional, and social abilities of our species. The basic mechanisms of early cortical development are believed to be ver...
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| Language: | English |
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Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2007.
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| Edition: | 1st ed. 2007. |
| Series: | Advances in Anatomy, Embryology and Cell Biology,
189 |
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| Online Access: | https://doi.org/10.1007/978-3-540-36689-8 |
Table of Contents:
- Materials and Methods
- The Anatomical Basis of Human Cortical Development
- Neuronal Miqration
- Compartments of the Cortical Wall
- The Cortical Hem: Signaling Center and Birthplace of CR Cells
- The Reelin-Dab1 Signaling Pathway
- The Cdk5/p35 Pathway
- LIS1 and DCX: Key Genes for Neuronal Migration and Cortical Folding
- ARX Deficiency: A Novel Type of Lissencephaly
- Final Considerations: The Unique Features of Human Brain Development.