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Biomedical Applications of Acridines Derivatives, Syntheses, Properties and Biological Activities with a Focus on Neurodegenerative Diseases /

This book describes applications of acridines for the treatment of various neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and various prion diseases, and discusses the potential of acridines in neuro-regenerative medicine. Using modern data-mining software, it presents...

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Main Authors: Ježek, Jan. (Author, http://id.loc.gov/vocabulary/relators/aut), Hlaváček, Jan. (http://id.loc.gov/vocabulary/relators/aut), Šebestík, Jaroslav. (http://id.loc.gov/vocabulary/relators/aut)
Corporate Author: SpringerLink (Online service)
Language:English
Published: Cham : Springer International Publishing : Imprint: Springer, 2017.
Edition:1st ed. 2017.
Series:Progress in Drug Research, 72
Subjects:
Medicinal chemistry.
Neurochemistry.
Pharmacology.
Proteins .
Bioorganic chemistry.
Nucleic acids.
Medicinal Chemistry.
Pharmacology/Toxicology.
Protein-Ligand Interactions.
Bioorganic Chemistry.
Nucleic Acid Chemistry.
Online Access:https://doi.org/10.1007/978-3-319-63953-6
Table of Contents:
  • Preliminary ToC 1 Introduction
  • 2 Nomenclature
  • 3. Syntheses
  • 4. Interactions of acridines with nucleic acids
  • 5. Intercations with proteins
  • 6. Applications for treament of neurodegenerative diseases
  • 7. Some applications of selective toxicities of acridines
  • 8. Acridine on dendrimeric carriers
  • 9 Acridines used for staining
  • 10 Miscellaneous
  • 11 Conclusions and outlook.

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