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G-Protein-Coupled Receptor Dimers

G-protein-coupled receptors (GPCRs) are believed to be the largest family of membrane proteins involved in signal transduction and cellular responses. They dimerize (form a pair of macromolecules) with a wide variety of other receptors. The proposed book will provide a comprehensive overview of GPCR...

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Corporate Author: SpringerLink (Online service)
Other Authors: Herrick-Davis, Katharine. (Editor, http://id.loc.gov/vocabulary/relators/edt), Milligan, Graeme. (Editor, http://id.loc.gov/vocabulary/relators/edt), Di Giovanni, Giuseppe. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Language:English
Published: Cham : Springer International Publishing : Imprint: Humana, 2017.
Edition:1st ed. 2017.
Series:The Receptors, 33
Subjects:
Neurosciences.
Online Access:https://doi.org/10.1007/978-3-319-60174-8
Table of Contents:
  • Part I. Introduction
  • 1. From Monomers to Dimers and Beyond: An Exciting Journey in the World of the G protein-coupled Receptor Family.- 2. The use of Spatial Intensity Distribution Analysis to Examine G protein-coupled Receptor Oligomerization
  • 3. Advanced Microscopy Techniques for Studying G protein-coupled Receptors.- Part II. Receptors.- 4. Light Sensing G protein-coupled Receptor Rhodopsin Dimer
  • 5. Extreme Vetting of Dopamine Receptor Oligomerization
  • 6. Serotonin receptors.- 7. Cannabinoid and Opioid Receptor Heteromers
  • 8. Di/oligomerization of Glycoprotein Hormone Receptors.- 9. Chemokine Receptor Oligomerization to Tweak Chemotactic Responses
  • 10. Secretin Receptor Dimerization. Prototypic of Class B GPCR Behavior.- 11. Receptors and RAMPs
  • 12. Obligatory Heterodimerization of GABAB Receptor.- 13. Metabotropic Glutamate Receptors. Part III. Assembly and Trafficking.- 14. The monomer/homodimer Equilibrium of G protein-coupled Receptors: Formation in the Secretory Pathway and Potential Functional Significance.- 15. Probing Self-assembly of G protein-coupled Receptor Oligomers in Membranes using Molecular Dynamics Modeling and Experimental Approaches.- 16. Interaction of Membrane Cholesterol with GPCRs: Implications in Receptor Oligomerization.- Part IV. Physiology and Therapeutic Potential.- 17. Allosterism within GPCR Oligomers: Back to Symmetry.- 18. Understanding the Physiological Significance of GPCR Dimers and Oligomers
  • 19. Heteromers form Novel Signaling Complexes
  • 20. Heteroreceptor Complexes Implicated in Parkinson’s Disease.

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