Bone Toxicology

The content of this book is intended to provide the toxicologist in drug development in the pharmaceutical and biotechnology industries with a broad understanding of bone and its interactions with other organ systems in safety assessments. The book is divided into three parts. The first part describ...

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Corporate Author: SpringerLink (Online service)
Other Authors: Smith, Susan Y. (Editor, http://id.loc.gov/vocabulary/relators/edt), Varela, Aurore. (Editor, http://id.loc.gov/vocabulary/relators/edt), Samadfam, Rana. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Language:English
Published: Cham : Springer International Publishing : Imprint: Springer, 2017.
Edition:1st ed. 2017.
Series:Molecular and Integrative Toxicology,
Subjects:
Online Access:https://doi.org/10.1007/978-3-319-56192-9
Table of Contents:
  • Bone Toxicology in Preclinical Drug Testing
  • Bone Physiology and Biology
  • Study designs and Regulatory Considerations
  • Specific Considerations for Bone Evaluations for Pediatric Therapeutics
  • Bone Pharmacology and other models in Preclinical Drug Testing
  • Methods in Bone Toxicology
  • Biochemical Markers and Hormones
  • Imaging
  • Biomechanics
  • Pathology and Histomorphometry
  • Integrated System Toxicology
  • Bone and Muscle
  • Bone and Reproductive System
  • Bone and Kidneys
  • Bone and Energy Metabolism
  • Bone and Immune System
  • Bone and Central Nervous System
  • Bone and Other Organs.