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Fundamentals of Pediatric Drug Dosing

Focused on pediatric physiology, pharmacology, pharmacokinetics and pharmacodynamics, this book illustrates the differences between the pediatric population and adults; knowledge of extreme importance not only during pediatric drug development but also in the clinical practice. Physicians, nurses, c...

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Corporate Author: SpringerLink (Online service)
Other Authors: Mahmood, Iftekhar. (Editor, http://id.loc.gov/vocabulary/relators/edt), Burckart, Gilbert. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Language:English
Published: Cham : Springer International Publishing : Imprint: Adis, 2016.
Edition:1st ed. 2016.
Subjects:
Pediatrics.
Pharmacotherapy.
General practice (Medicine).
General Practice / Family Medicine.
Online Access:https://doi.org/10.1007/978-3-319-43754-5
Table of Contents:
  • 1. Pediatric Drug Development and the Regulatory Changes that are Creating the Science of Pediatric Dosing
  • 2. Pediatric Physiology
  • 3. Developmental Pharmacology: Impact on Pharmacokinetics and Pharmacodynamics of Drugs
  • 4. Pediatric Clinical Trial Design and Dosing
  • 5. Applicaton of Allometric Principles in Pediatric Drug Development
  • 6. Population Pharmacokinetics in Pediatric Drug Development
  • 7. Scaling Dose-Exposure-Response from Adults to Children
  • 8. Applications of Physiologically-Based Pharmacokinetic (PBPK) Models for Pediatric Populations
  • 9. Perinatal Pharmacology and Maternal/Fetal Dosing.

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