Fundamentals of Neurodegeneration and Protein Misfolding Disorders
This unique text introduces students and researchers to the world of misfolded proteins, toxic oligomers, and amyloid assemblages, and the diseases of the brain that result. During the past few years the connections between failures in protein quality control and neurological disorders have been rei...
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| Language: | English |
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Cham :
Springer International Publishing : Imprint: Springer,
2015.
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| Edition: | 1st ed. 2015. |
| Series: | Biological and Medical Physics, Biomedical Engineering,
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| Online Access: | https://doi.org/10.1007/978-3-319-22117-5 |
Table of Contents:
- Introduction
- Protein Folding, Part I: Basic Principles
- Protein Folding, Part II: Energy Landscapes and Protein Dynamics
- Protein Misfolding and Aggregation
- Protein Quality Control, Part I: Molecular Chaperones and the Ubiquitin-Proteasome System
- Protein Quality Control, Part II: Autophagy and Aging
- Prion Diseases
- Alzheimer’s Disease
- Parkinson’s Disease
- Huntington’s Disease and other Unstable Repeat Disorders
- Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration.