Human Papillomavirus (HPV)-Associated Oropharyngeal Cancer

Head and neck squamous cell carcinoma (HNSCC), the sixth most prevalent cancer worldwide, remains a very difficult disease to treat and cure despite intensive investigation into molecular etiologies and tumor progression pathways. Due to public health efforts encouraging smoking cessation, the overa...

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Corporate Author: SpringerLink (Online service)
Other Authors: Miller, Daniel L. (Editor, http://id.loc.gov/vocabulary/relators/edt), Stack, M. Sharon. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Language:English
Published: Cham : Springer International Publishing : Imprint: Springer, 2015.
Edition:1st ed. 2015.
Subjects:
Online Access:https://doi.org/10.1007/978-3-319-21100-8
Table of Contents:
  • Epidemiology of HPV-Associated Oropharyngeal Squamous Cell Carcinoma
  • Behavioral Correlates of HPV-Associated Oropharyngeal Squamous Cell Carcinomas
  • Racial Disparities in Oropharyngeal Cancer
  • HPV Virology: Cellular Targets of HPV Oncogenes and Transformation
  • Papillomavirus Replication
  • MicroRNA Profiles of HPV-Associated  Oropharyngeal Squamous Cell Carcinoma (OPSCC)
  • Targeting the PI3K-mTOR Signaling Circuitry in HPV-Associated Oral Malignancies: Novel Precision Molecular Therapies
  • Mutational Profile of HPV-Positive HNSCC
  • Clinical Presentation of HPV-driven Oropharyngeal Carcinoma
  • Differences and Similarities between HPV-Associated OPSCC and Cervical Cancer
  • Surgical Perspective in the Management of Oropharyngeal Cancer
  • HPV and Radiation Sensitivity
  • The Role of Immune Modulation in the Carcinogenesis and Treatment of HPV-associated Oropharyngeal Cancer.