Animal Cell Culture
Animal cells are the preferred “cell factories” for the production of complex molecules and antibodies for use as prophylactics, therapeutics or diagnostics. Animal cells are required for the correct post-translational processing (including glycosylation) of biopharmaceutical protein products. They...
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| Language: | English |
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Cham :
Springer International Publishing : Imprint: Springer,
2015.
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| Edition: | 1st ed. 2015. |
| Series: | Cell Engineering,
9 |
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| Online Access: | https://doi.org/10.1007/978-3-319-10320-4 |
Table of Contents:
- Preface
- 1 Cell line development
- 2 Transient recombinant protein expression in mammalian cells
- 3 Hybridoma technology for the in vitro production of therapeutic antibodies
- 4 Bioreactors for mammalian cells
- 5 Mass Transfer and Mixing Across the Scales in Animal Cell Culture
- 6 Hydrodynamic Damage to Animal Cells
- 7 Monitoring of cell culture
- 8 Serum and protein free media
- 9 Glycosylation in Cell Culture
- 10 Modelling of mammalian cell cultures
- 11 Mammalian Cell Line Selection Strategies for High-Producers
- 12 Building a Cell Culture Process with Stable Foundations: Searching for Certainty in an Uncertain World
- 13 Perfusion Processes
- 14 Single-use bioreactors for animal and human cells
- 15 An Overview of Cell Culture Engineering for the Insect Cell-Baculovirus Expression Vector System (BEVS)
- 16 Metabolic flux analysis: a powerful tool in animal cell culture
- 17 Cell immobilization for the production of viral vaccines
- 18 Cell Engineering for Therapeutic Protein Production
- 19 Proteomics in Cell Culture: From genomics to combined ‘omics for cell line engineering and bioprocess development
- 20 Metabolomics in animal cell culture
- 21 Process Analytical Technology and Quality-by-Design for Animal Cell Culture
- 22 Biosafety recommendations on the handling of animal cell cultures
- 23 Biopharmaceutical products from animal cell culture
- Index.