Drugs Targeting B-Cells in Autoimmune Diseases

This book provides a detailed overview of B-cell directed therapies in patients with rheumatic and systemic autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, Sjögren syndrome, ANCA-associated vasculitis and cryoglobulinemia. Organ-specific autoimmune diseases are dis...

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Corporate Author: SpringerLink (Online service)
Other Authors: Bosch, Xavier. (Editor, http://id.loc.gov/vocabulary/relators/edt), Ramos-Casals, Manuel. (Editor, http://id.loc.gov/vocabulary/relators/edt), Khamashta, Munther A. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Language:English
Published: Basel : Springer Basel : Imprint: Springer, 2014.
Edition:1st ed. 2014.
Series:Milestones in Drug Therapy,
Subjects:
Online Access:https://doi.org/10.1007/978-3-0348-0706-7
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490 1 |a Milestones in Drug Therapy,  |x 2296-6056 
505 0 |a Historic outline of the development of drugs targeting B-cells -- Understanding B-cell biology -- Pharmacological effects and mechanisms of action of agents blocking B cells -- Systemic lupus erythematosus: direct B-cell blocking -- Systemic lupus erythematosus: indirect B-cell blocking -- B-cell targeted therapies in rheumatoid arthritis -- B-cell targeted therapies in Primary Sjögren Syndrome -- Targeting B cells in ANCA-associated vasculitis -- B-cell targeted therapies in systemic sclerosis and inflammatory myopathies -- B-cell targeted therapies in cryoglobulinemia -- B-cell targeted therapies in autoimmune cytopenias and thrombosis -- Targeting B cells in neurological autoimmune diseases -- Targeting B cells in other systemic autoimmune diseases -- Safety of B-cell targeted therapies -- The future potential of biosimilars targeting B-cells. 
520 |a This book provides a detailed overview of B-cell directed therapies in patients with rheumatic and systemic autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, Sjögren syndrome, ANCA-associated vasculitis and cryoglobulinemia. Organ-specific autoimmune diseases are discussed with respect to the use of B-cell directed therapies in neurological autoimmune diseases and autoimmune cytopenias. Situations in which B-cell targeted therapy may be indicated are identified, thereby offering comprehensive support for therapeutic decisions on the basis of the latest published evidence. The book also offers a valuable reference tool for rheumatologists, internists, nephrologists, immunologists, and all specialists involved in the multidisciplinary care of patients with rheumatic and systemic autoimmune diseases. 
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