Introduction to Antibody Engineering

This highly readable textbook serves as a concise and engaging primer to the emerging field of antibody engineering and its various applications. It introduces readers to the basic science and molecular structure of antibodies, and explores how to characterize and engineer them. Readers will find an...

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Corporate Author: SpringerLink (Online service)
Other Authors: Rüker, Florian. (Editor, http://id.loc.gov/vocabulary/relators/edt), Wozniak-Knopp, Gordana. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Language:English
Published: Cham : Springer International Publishing : Imprint: Springer, 2021.
Edition:1st ed. 2021.
Series:Learning Materials in Biosciences,
Subjects:
Online Access:https://doi.org/10.1007/978-3-030-54630-4
Table of Contents:
  • Chapter 1. Introduction by the editors
  • Chapter 2. Antibodies – A History of their Discovery and Properties
  • Chapter 3. Monoclonal Antibodies and Hybridomas
  • Chapter 4. Antibody Display Systems
  • Chapter 5. Transgenic Animals for the Generation of Human Antibodies
  • Chapter 6. Applications of Antibodies in Therapy, Diagnosis & Science
  • Chapter 7. Bispecific antibodies
  • Chapter 8. Antibody-Drug Conjugates
  • Chapter 9. Alternative Binding Scaffolds – multipurpose binders for applications in basic research and therapy
  • Chapter 10: Chimeric antigen receptor (CAR) redirected T cells
  • Chapter 11. Improvement of Key Characteristics of Antibodies
  • Chapter 12. Engineering therapeutic antibodies for development
  • Chapter 13. Eukaryotic expression systems for upstream pro-cessing of monoclonal antibodies
  • Chapter 14. Antibody Validation.