Mechanisms of Genome Protection and Repair

This volume is about DNA damage and repair. It covers recent advances in several important research areas of this rapidly expanding field, and does so at several levels, from individual molecules to organisms. The topics include mechanisms of damage recognition by DNA repair enzymes, chromatin respo...

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Corporate Author: SpringerLink (Online service)
Other Authors: Zharkov, Dmitry O. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Language:English
Published: Cham : Springer International Publishing : Imprint: Springer, 2020.
Edition:1st ed. 2020.
Series:Advances in Experimental Medicine and Biology, 1241
Subjects:
Online Access:https://doi.org/10.1007/978-3-030-41283-8
Table of Contents:
  • Preface
  • Kinetic Milestones of Damage Recognition by DNA Glycosylases of the Helix–Hairpin–Helix Structural Superfamily
  • Protein Engineering of DNA-Dependent Enzymes
  • A Multifunctional Protein PolDIP2 in DNA Translesion Synthesis
  • Impact of PARP1, PARP2 and PARP3 on the Base Excision Repair of Nucleosomal DNA
  • Base Excision Repair in Chromatin and the Requirement for Chromatin Remodelling
  • DNA Repair and Mutagenesis in Vertebrate Mitochondria: Evidence for Asymmetric DNA Strand Inheritance
  • Mystery of Expansion: DNA Metabolism and Unstable Repeats
  • The Detection of 8-Oxo-7,8-Dihydro-2′-Deoxyguanosine in Circulating Cell-Free DNA: A Step Towards Longitudinal Monitoring of Health
  • Biotransformation and Toxicities of Aristolochic Acids
  • Mechanisms of Sugar Beet Response to Biotic and Abiotic Stresses
  • Studying ALS: Current Approaches, Effect on Potential Treatment Strategy.