Mammalian Sterols Novel Biological Roles of Cholesterol Synthesis Intermediates, Oxysterols and Bile Acids /

This book provides a comprehensive description of sterols and their novel biological roles in mammalian signaling, the book covers their biosynthesis and structure, describes sterol receptor -mediated actions, their tissue distribution and their role in disease. It offers insight into new research f...

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Corporate Author: SpringerLink (Online service)
Other Authors: Rozman, Damjana. (Editor, http://id.loc.gov/vocabulary/relators/edt), Gebhardt, Rolf. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Language:English
Published: Cham : Springer International Publishing : Imprint: Springer, 2020.
Edition:1st ed. 2020.
Subjects:
Online Access:https://doi.org/10.1007/978-3-030-39684-8
Table of Contents:
  • Sterols from the post-lanosterol part of cholesterol synthesis – novel signaling players
  • Genetic variability in cholesterol metabolism
  • Side-chain oxidized oxysterols in health and disease
  • Bile acids and TGR5 (Gpbar1) signaling
  • Bile acids as regulatory signalling molecules
  • Oxysterols and bile acid act as signaling molecules that regulate cholesterol homeostasis: nuclear receptors LXR, FXR, and fibroblast growth factor 15/19
  • Cytochrome P450 Metabolism Leads to Novel Biological Sterols and Other Steroids.