Activity-Based Protein Profiling

This volume provides a collection of contemporary perspectives on using activity-based protein profiling (ABPP) for biological discoveries in protein science, microbiology, and immunology. A common theme throughout is the special utility of ABPP to interrogate protein function and small-molecule int...

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Corporate Author: SpringerLink (Online service)
Other Authors: Cravatt, Benjamin F. (Editor, http://id.loc.gov/vocabulary/relators/edt), Hsu, Ku-Lung. (Editor, http://id.loc.gov/vocabulary/relators/edt), Weerapana, Eranthie. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Language:English
Published: Cham : Springer International Publishing : Imprint: Springer, 2019.
Edition:1st ed. 2019.
Series:Current Topics in Microbiology and Immunology, 420
Subjects:
Online Access:https://doi.org/10.1007/978-3-030-11143-4
Table of Contents:
  • Activity-based protein profiling – enabling multimodal functional studies of microbial communities
  • Activity-Based Protein Profiling Methods to Study Bacteria: The Power of Small-Molecule Electrophiles
  • Opportunities and Challenges in Activity-Based Protein Profiling of Mycobacteria
  • Activity-Based Protein Profiling at the Host–Pathogen Interface
  • Chemical Proteomic Profiling of Protein Fatty-Acylation in Microbial Pathogens
  • How to Target Viral and Bacterial Effector Proteins Interfering with Ubiquitin Signaling
  • ABPP and Host–Virus Interactions
  • Activity-Based Protein Profiling for the Study of Parasite Biology
  • Deciphering T Cell Immunometabolism with Activity-Based Protein Profiling
  • Small-Molecule Inhibitors of PARPs: From Tools for Investigating ADP-Ribosylation to Therapeutics
  • Development of Activity-Based Proteomic Probes for Protein Citrullination
  • Recent Advances in Activity-Based Protein Profiling of Proteases
  • Opportunities for Lipid-Based Probes in the Field of Immunology
  • Activity-Based Protein Profiling of Non-ribosomal Peptide Synthetases
  • Target Identification of Bioactive Covalently Acting Natural Products
  • Applications of Reactive Cysteine Profiling.