Cholesterol Modulation of Protein Function Sterol Specificity and Indirect Mechanisms /
In this book, renowned scientists describe the role of steroid chirality and modification of lipid membrane physical properties in the modulation of G protein-coupled receptors and ion channels. The application of commonly-used technical approaches such as mass spectrometry and nucleic magnetic reso...
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| Other Authors: | , |
| Language: | English |
| Published: |
Cham :
Springer International Publishing : Imprint: Springer,
2019.
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| Edition: | 1st ed. 2019. |
| Series: | Advances in Experimental Medicine and Biology,
1115 |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/978-3-030-04278-3 |
Table of Contents:
- Part 1. Sterol specificity in modulating protein function: 1. Chirality effect on cholesterol modulation of protein function
- 2. A critical analysis of molecular mechanisms underlying membrane cholesterol sensitivity of GPCRs
- 3. Regulation of BK channel activity by cholesterol and its derivatives
- 4. Chiral specificity of cholesterol orientation within cholesterol binding sites in inwardly rectifying potassium channels
- Part 2. Indirect modulation of protein function by cholesterol: 5. Cholesterol effect on the physical properties of lipid membranes
- 6. Effect of cholesterol on the dipole potential of lipid membranes
- 7. Mass spectroscopy imaging of cholesterol
- 8. Cholesterol-dependent gating effects on ion channels.