Gold(I,III) Complexes Designed for Selective Targeting and Inhibition of Zinc Finger Proteins
This book examines Au (I, III) complexes that selectively attack and inhibit zinc finger proteins (ZnFs) for potential therapeutic use. The author explores gold(I)-phosphine, gold(III) complexes with N^N and C^N donors as inhibitors of the HIV-1 nucleocapsid protein (NCp7), in comparison to the huma...
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| Language: | English |
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Cham :
Springer International Publishing : Imprint: Springer,
2018.
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| Edition: | 1st ed. 2018. |
| Series: | Springer Theses, Recognizing Outstanding Ph.D. Research,
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| Online Access: | https://doi.org/10.1007/978-3-030-00853-6 |
Table of Contents:
- Au(I)-phosphine series design
- Probing the Protein: Ion Mobility Spectrometry
- Probing Gold: X-ray Absorption Spectroscopy
- Probing Cells: Cytotoxicity Evaluation
- Au(III) series with k2C,N and k2N,N' ligands
- "Dual Probe" X-ray Absorption Spectroscopy.