Discoidin Domain Receptors in Health and Disease
The interactions of cells with their surrounding extracellular matrix (ECM) plays a pivotal role in driving normal cell behavior, from development to tissue differentiation and function. At the cellular level, organ homeostasis depends on a productive communication between cells and ECM, which event...
Corporate Author: | |
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Other Authors: | , |
Language: | English |
Published: |
New York, NY :
Springer New York : Imprint: Springer,
2016.
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Edition: | 1st ed. 2016. |
Subjects: | |
Online Access: | https://doi.org/10.1007/978-1-4939-6383-6 |
Table of Contents:
- Part I: Discoidin Domain Receptor biology and roles in physiology
- DDRs: Binding properties, cell adhesion and modulation of integrin function
- DDRs and collagen fibrillogenesis
- DDR Structural Biology
- DDR Mouse models
- DDR in Invertebrates
- Part II: Discoidin Domain Receptors in Cancer
- Discoidin Domain Receptors and Disease
- Discoidin Domain Receptors in Normal Mammary Development and Breast Cancer Progression
- Discoidin Domain Receptors in Lung Cancer
- DDRs in healthy and cancerous reproductive systems
- Small Molecule Inhibitors of Discoidin Domain Receptors
- Discoidin Domain Receptor Signaling Networks
- Discoidin Domain Receptor Signaling and Pharmacological Inhibitors
- Functions of DDR1 in epithelial cell differentiation
- Part III: Discoidin Domain Receptors in other pathologies
- Discoidin Domain Receptor 2 in Development of Osteoarthritis
- DDR1 in Renal Function and Disease
- Discoidin Domain Receptors in Liver Fibrosis
- The role of DDRs in Atherosclerosis
- Discoidin Domain Receptors in Cardiac Development.