Macrophages: Biology and Role in the Pathology of Diseases
Macrophages are a key component of the innate immune system and play an integral role in host defense and homeostasis. On one hand, these cells contribute to host defence by triggering inflammation, displaying microbicidal/tumoricidal properties, regulating the activation of adaptive immunity and pr...
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| Other Authors: | , |
| Language: | English |
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New York, NY :
Springer New York : Imprint: Springer,
2014.
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| Edition: | 1st ed. 2014. |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/978-1-4939-1311-4 |
Table of Contents:
- Part I Macrophage: Origin, Activation And Polarization
- Blood monocytes and their subsets in health and disease
- Polarized activation of macrophages
- Alternative activation of macrophages: concepts and prospects
- Regulatory macrophages and the maintenance of homeostasis
- Part II Macrophages And Their Diverse Functions
- Phagocytosis
- The antimicrobial functions of macrophages
- Vascular modulatory functions of macrophages
- Part III Macrophages In Different Tissues
- Airway macrophages: sentinels of health
- Microglial ontogeny and functions in shaping brain circuits
- Kupffer cells in health and disease
- Intestinal Macrophages: Specialized antigen-presenting cells at the front line
- Part IV Macrophages In Pathology
- The wound macrophage - Macrophages and the entrance of resolution phase lipid mediators
- Macrophages in sepsis progression
- Adaptive characteristics of innate immune responses in macrophages
- African trypanosomiasis as paradigm for involvement of the mononuclear phagocyte system in pathogenicity during parasite infection
- Macrophages in obesity and insulin resistance
- Macrophages govern the progression and termination of inflammation in atherosclerosis and metabolic diseases
- Myelomonocytic subsets in tumor microenvironment
- Tumor associated macrophages
- Part V Transcriptional And Epigenetic Mechanisms
- Role of NF-kB activation in macrophages
- Interferon Regulatory Factors: Role in transcriptional regulation of macrophage plasticity and activation
- Kruppel-like factors in Monocyte-Macrophage Biology
- Regulation of macrophage polarization by the STAT-SOCS signaling axis
- Functions of the large Maf transcription factors and macrophages
- The Control of Gene Expression in Macrophages
- Role of microRNA in macrophage activation and polarization
- Part VI Systems Biology Of Macrophages
- The macrophage transcriptome
- Omics approaches in macrophage biology
- Appendix.