Cardiac Energy Metabolism in Health and Disease
The heart has a very high energy demand but very little energy reserves. In order to sustain contractile function, the heart has to continually produce a large amount of ATP. The heart utilizes free fatty acids mainly and carbohydrates to some extent as substrates for making energy, and any change...
| Corporate Author: | |
|---|---|
| Other Authors: | , |
| Language: | English |
| Published: |
New York, NY :
Springer New York : Imprint: Springer,
2014.
|
| Edition: | 1st ed. 2014. |
| Series: | Advances in Biochemistry in Health and Disease,
11 |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/978-1-4939-1227-8 |
Table of Contents:
- Part 1. Control of Energy Metabolism
- 1. A Primer on Carbohydrate Metabolism in the Heart
- 2. Lipoproteins: A Source of Cardiac Lipids
- 3. Role of Lipoprotein Lipase in Fatty Acid Delivery to the Heart
- 4. Control of Myocardial Fatty Acid Uptake
- 5. Cardiac Energy Metabolism in Heart Failure Associated with Obesity and Diabetes
- 6. Transcriptional Control of Mitochondrial Biogenesis and Maturation
- 7. Relationship between Substrate Metabolism and Cardiac Efficiency
- 8. Acetylation in the Control of Mitochondrial Metabolism and Integrity
- Part 2. Alteration in Energy Metabolism
- 9. Adrenergic Control of Cardiac Fatty Acid Oxidation in Diabetes
- 10. The Myocardial Creatine Kinase System in the Normal, Ischaemic and Failing Heart
- 11. Fuel Metabolism Plasticity in Pathological Cardiac Hypertrophy and Failure
- 12. Defects in Mitochondrial Oxidative Phosphorylation in Hearts Subjected to Ischemia-Reperfusion Injury
- 13. The Role of AMPK in the Control of Cardiac Hypertrophy
- 14. The Role of Incomplete Fatty Acid Oxidation in the Development of Cardiac Insulin Resistance
- Part 3. Optimization of Energy Metabolism
- 15. Metabolic Therapy for the Ischemic Heart
- 16. Inhibition of Fatty Acid Oxidation to Treat Heart Failure in Patients
- 17. Cardiac Metabolic Protection for the Newborn Heart
- 18. Targeting Transcriptional Control of Fatty Acid Oxidation to Treat Heart Disease.