Cell Death Mechanism and Disease /

Beginning from centuries of anecdotal descriptions of cell death, such as those on the development of the midwife toad in 1842 by Carl Vogt, to modern-day investigations of cell death as a biological discipline, it has become accepted that cell death in multicellular organisms is a normal part of li...

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Corporate Author: SpringerLink (Online service)
Other Authors: Wu, Hao. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Language:English
Published: New York, NY : Springer New York : Imprint: Springer, 2014.
Edition:1st ed. 2014.
Subjects:
Online Access:https://doi.org/10.1007/978-1-4614-9302-0
Table of Contents:
  • 1. Historical Perspective – the Seven Ages of Cell Death Research
  • 2. The Intrinsic Apoptotic Pathway
  • 3. Molecular Basis of Cell Death Programs in Mature T Cell Homeostasis
  • 4. Bcl-2 family and their therapeutic potential
  • 5. IAP proteins and their therapeutic potential
  • 6. Cell Death and Cancer
  • 7. The DNA damage response mediates apoptosis and tumor suppression
  • 8. Neuronal Death Mechanisms in Development and Disease
  • 9. The Complex Interplay Between Metabolism and Apoptosis
  • 10. Programmed Necrosis/Necroptosis: An Inflammatory Form of Cell Death
  • 11. Structural Perspectives on BCL-2 Family of Proteins
  • 12. Structural basis of death receptor signaling.