Advances in Biology and Therapy of Multiple Myeloma Volume 1: Basic Science /
Despite the advances in conventional, and novel agent and high dose chemotherapy, multiple myeloma remains incurable. In order to overcome resistance to current therapies and improve patient outcome, novel biologically-based treatment approaches are being developed. Current translational research in...
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| Other Authors: | , |
| Language: | English |
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New York, NY :
Springer New York : Imprint: Springer,
2013.
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| Edition: | 1st ed. 2013. |
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| Online Access: | https://doi.org/10.1007/978-1-4614-4666-8 |
Table of Contents:
- Genomic strategies determining progressions from MGUS to Multiple Myeloma
- Prognostic implication of Genetic changes (Cytogenetics, and FISH, gains and losses of DNA by SNP array and aCGH) in risk stratification in myeloma
- Advances in MM gene expression profiling
- Growth factors in MM
- Role of Wnt signaling pathways in multiple myeloma pathogenesis
- mTOR pathway in multiple myeloma
- Jak/STAT signaling in the pathogenesis and treatment of multiple myeloma
- Role of extracellular matrix in myeloma biology
- Osteoclasts: Potential target for blocking microenvironmental support of myeloma
- Targeting the BAFF/APRIL cytokine network in multiple myeloma
- Role of Osteoblast in myeloma pathology
- Migration and homing in Multiple Myeloma
- Genes and proteins of myeloma endothelial cells to search specific targets of the tumor vasculature
- Epigenetic regulation of myeloma within its bone marrow microenvironment
- Targeting mulitple myeloma tumor angiogenesis: focus on VEGF
- Novel in vivo model in myeloma
- Index.