Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics

Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal...

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Corporate Author: SpringerLink (Online service)
Other Authors: Vinks, Alexander A. (Editor, http://id.loc.gov/vocabulary/relators/edt), Derendorf, Hartmut. (Editor, http://id.loc.gov/vocabulary/relators/edt), Mouton, Johan W. (Editor, http://id.loc.gov/vocabulary/relators/edt)
Language:English
Published: New York, NY : Springer New York : Imprint: Springer, 2014.
Edition:1st ed. 2014.
Subjects:
Online Access:https://doi.org/10.1007/978-0-387-75613-4
Table of Contents:
  • Foreword
  • Section I: Basic Concepts and Principles
  • Introduction to Pharmacodynamics and micrbiology
  • In vitro and animal PK/PD model
  • MIC and breakpoints
  • Principles of applied PK/PD modeling
  • Population Pk/PD modeling and its applications to antimicrobials
  • Drug resistance and Drug-drug combinations
  • Section II: Clinical
  • Aminoglycosides
  • Beta-lactam antibiotics including continuous infusion
  • Macrolides
  • Glycopeptides
  • Quinolones
  • Other.-      .