04397cam a2200469Ii 4500 on1223026058 OCoLC 20210423014357.0 m o d cr ||||||||||| 200911s2020 ne fo 000 0 eng d UKAHL eng rda UKAHL EBLCP OPELS OCLCO N$T OCLCF UKMGB GBC0E3330 bnb 019949177 Uk 0128192631 (e-book) 9780128192634 (electronic bk.) 9780128192627 (pbk.) (OCoLC)1223026058 QH457 155.7 Developmental human behavioral epigenetics principles, methods, evidence, and future directions / edited by Livio Provenzi, Rosario Montirosso. Amsterdam : Academic Press, 2020. 1 online resource text txt rdacontent computer c rdamedia online resource cr rdacarrier Translational epigenetics ; 23 Intro -- Developmental Human Behavioral Epigenetics: Principles, Methods, Evidence, and Future Directions -- Copyright -- Contents -- Contributors -- Keeping complexity in mind -- References -- Section I: Introduction -- Chapter 1: Principles of epigenetics and DNA methylation -- Definition of epigenetics -- Types of epigenetic modifications -- DNA cytosine methylation -- DNA cytosine hydroxymethylation -- DNA adenosine methylation -- RNA modifications -- Histone modifications -- RNAs -- Environmental effects, cell metabolism and epigenetics -- Epigenetic memory -- Environmental effects Cell metabolism, diet and microbiota -- Methods for methylation analysis -- Chromatin immunoprecipitation -- Nucleosome positioning -- DNA cytosine methylation analysis -- Locus-specific DNA methylation analysis -- Whole methylome analysis -- Selected genome-wide methylation analysis -- Epigenotyping arrays -- Direct readout of DNA methylation -- DNA methylation analysis of cell-free circulating DNA -- Single-cell epigenomics -- References -- Chapter 2: From animal to human epigenetics -- A rat story: Behavioral epigenetics beginnings Post-natal maternal environment shapes the epigenome and adult behavioral phenotypes of the offspring -- Environmental stimuli delivered to parents trigger processes to transmit information to offspring -- Permissive environments -- Environmental enrichment -- Maternal enrichment during pregnancy and/or lactation -- Pre-reproductive parental enrichment -- Aversive environments -- Aversive environment: Animal studies -- Epigenetic perturbation can be passed along -- Combining human and non-human animal research -- References -- Chapter 3: An overview of developmental behavioral genetics Background/history -- Behavioral genetic methodology -- Key interpretative issues -- Key results from twin and adoption studies -- Gene-environment interplay -- Gene-environment correlation -- Passive rGE -- Active rGE -- Evocative rGE -- Gene-environment interaction -- Genomic approaches to behavioral genetics -- Concluding remarks -- References -- Section II: Behavioral epigenetics in action -- Chapter 4: Prenatal exposures and behavioral epigenetics in human infants and children -- Early environmental programming -- Biological embedding Fetal DNA methylation after exposure to prenatal stress -- Does DNA methylation at birth predict postnatal outcomes? -- Further directions -- References -- Chapter 5: Applying behavioral epigenetic principles to preterm birth and early stress exposure -- Introduction -- Background -- Epigenetic regulation by early adverse experiences -- Epigenetic regulation by early protective experiences -- Preterm birth and NICU-related early adverse experiences -- Preterm birth and NICU-related early protective experiences -- A rationale for preterm behavioral epigenetics -- State of the art of PBE research Behavior genetics. Epigenetics. Behavior genetics. fast (OCoLC)fst00829913 Epigenetics. fast (OCoLC)fst01893642 Electronic books. Electronic books. Provenzi, Livio, editor. Montirosso, Rosario, editor. Print version : 9780128192627 ScienceDirect https://www.sciencedirect.com/science/book/9780128192627