03692nam a22005535i 4500 978-3-319-39537-1 DE-He213 20210620011631.0 cr nn 008mamaa 160606s2016 gw | s |||| 0|eng d 9783319395371 978-3-319-39537-1 10.1007/978-3-319-39537-1 doi QC474-496.9 R895-920 PHVD bicssc SCI058000 bisacsh MKSH thema PNRL thema 610.153 23 Scherer, Kai Hermann. author. aut http://id.loc.gov/vocabulary/relators/aut Grating-Based X-Ray Phase-Contrast Mammography [electronic resource] / by Kai Hermann Scherer. 1st ed. 2016. Cham : Springer International Publishing : Imprint: Springer, 2016. XX, 140 p. 47 illus., 33 illus. in color. online resource. text txt rdacontent computer c rdamedia online resource cr rdacarrier text file PDF rda Springer Theses, Recognizing Outstanding Ph.D. Research, 2190-5053 Introduction -- Theoretical Background -- Experimental Setup & Methods Development -- Bi-directional Phase-Contrast Mammography -- Screening Value of Phase-Contrast Mammography -- Microcalcification Assessment with Dark-Field Mammography -- Toward Clinically Compatible Phase-Contrast Mammography -- Non-invasive Kidney Stone Differentiation Using Dark-Field Radiography -- Summary & Outlook. This thesis offers an accessible guide to biomedical phase-contrast imaging with over 20 radiographic illustrations. It focuses on research to improve radiography, and particularly mammography applications, by using a novel X-ray imaging modality that exploits the wave-nature of X-rays, rather than just their absorption in tissue. Further, it explores a broad range of potential applications – from the assessment of breast cancer and the evaluation of microcalcification clusters, to the examination of renal stones. X-ray imaging is an indispensable tool in modern medical diagnostics, and ranges from simple radiography applications to advanced CT imaging protocols. This novel phase-contrast approach has the potential to deliver significantly improved diagnostic information, also and especially in cases where mammography is used for screening purposes. The thesis is based on several studies conducted by the author – working in close interdisciplinary cooperation with medical doctors at two university clinics in Munich – and successfully demonstrates this diagnostic potential in pre-clinical experiments. Medical physics. Radiation. Radiology. Cancer research. Medical and Radiation Physics. https://scigraph.springernature.com/ontologies/product-market-codes/P27060 Diagnostic Radiology. https://scigraph.springernature.com/ontologies/product-market-codes/H29013 Cancer Research. https://scigraph.springernature.com/ontologies/product-market-codes/B11001 SpringerLink (Online service) Springer Nature eBook Printed edition: 9783319395364 Printed edition: 9783319395388 Printed edition: 9783319819082 Springer Theses, Recognizing Outstanding Ph.D. Research, 2190-5053 https://doi.org/10.1007/978-3-319-39537-1 ZDB-2-PHA ZDB-2-SXP Physics and Astronomy (SpringerNature-11651) Physics and Astronomy (R0) (SpringerNature-43715)